Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 15/20 | 0.83 |
| ▸ | GALR1 | P47211 | 9/20 | 0.83 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143793 | 0.91 | GALR2 (1.00) | GALR2GALR1NPSR1 | |
| SCHEMBL10143419 | 0.88 | GALR2 (0.81) | GALR2GALR1ABL1BCR | |
| SCHEMBL10143409 | 0.85 | GALR2 (0.82) | GALR2GALR1 | |
| SCHEMBL10143796 | 0.84 | GALR2 (1.00) | GALR2GALR1NPSR1LMNA | |
| SCHEMBL10144353 | 0.83 | GALR2 (1.00) | GALR2GALR1NPSR1LMNA | |
| SCHEMBL14503014 | 0.81 | GALR2 (0.61) | GALR2GALR1BACE1NPSR1LMNA | |
| SCHEMBL4356830 | 0.81 | GALR2 (0.57) | GALR2GALR1BACE1LMNATP53 | |
| SCHEMBL10144350 | 0.81 | GALR2 (0.72) | GALR2GALR1NPSR1LMNAABL1 | |
| SCHEMBL3996030 | 0.80 | GALR2 (0.55) | GALR2GALR1LMNATP53THRB | |
| SCHEMBL10144345 | 0.78 | GALR2 (0.71) | GALR2GALR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |