Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.68 |
| ▸ | MTOR | P42345 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.61 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27177842 | 0.83 | NPC1 (0.74) | ESRRGMTORMAPTRAB9ANPC1 | |
| SCHEMBL27177840 | 0.83 | NPC1 (0.74) | ESRRGMTORMAPTRAB9ANPC1 | |
| SCHEMBL15290016 | 0.80 | ESRRG (0.63) | ESRRGMTORMAPTRAB9ANPC1 | |
| SCHEMBL27177830 | 0.80 | RAB9A (0.64) | ESRRGMAPTRAB9ANPC1GAA | |
| SCHEMBL27177828 | 0.80 | RAB9A (0.64) | ESRRGMAPTRAB9ANPC1GAA | |
| SCHEMBL12443564 | 0.78 | GPR39 (0.81) | ESRRGMAPTRAB9ANPC1GAA | |
| SCHEMBL28879744 | 0.77 | HPGD (0.66) | ESRRGMTORMAPTRAB9ANPC1 | |
| SCHEMBL19283334 | 0.76 | KDM1A (0.74) | ESRRGMTORMAPTRAB9ANPC1 | |
| SCHEMBL19283335 | 0.76 | KDM1A (0.74) | ESRRGMTORMAPTRAB9ANPC1 | |
| SCHEMBL6569073 | 0.76 | KDM1A (0.74) | ESRRGMTORMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | ESRRG 2381/4885MTOR 2331/4885MAPT 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.