Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | DUSP3 | P51452 | 1/20 | 1.00 |
| ▸ | PTPN5 | P54829 | 1/20 | 1.00 |
| ▸ | PTPN11 | Q06124 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916246 | 0.87 | MAPT (0.78) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL3916303 | 0.85 | REV1 (0.79) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5455162 | 0.84 | MAPT (0.72) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5447380 | 0.84 | MAPT (0.72) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL8288668 | 0.83 | MAPT (0.71) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5459858 | 0.82 | MAPT (0.70) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5453347 | 0.82 | REV1 (0.76) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5453301 | 0.82 | REV1 (0.76) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5451305 | 0.82 | MAPT (0.70) | MAPTDUSP3PTPN5PTPN11POLB | |
| SCHEMBL5456030 | 0.82 | MAPT (0.70) | MAPTDUSP3PTPN5PTPN11POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPT 2982/4885DUSP3 1484/4885PTPN5 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.