Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.98 |
| ▸ | HPGD | P15428 | 13/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.98 |
| ▸ | TSHR | P16473 | 7/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | PHGDH | O43175 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288738 | 0.85 | HPGD (0.74) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL5449432 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL5456095 | 0.72 | ALDH1A1 (0.77) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL3455406 | 0.71 | KMT2A (0.72) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL3455797 | 0.71 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL3456893 | 0.71 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL19066920 | 0.71 | PHGDH (1.00) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL3455394 | 0.70 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL15272557 | 0.70 | CYBB (1.00) | ALDH1A1HPGDKDM4ETSHRMAPK1 | |
| SCHEMBL4140119 | 0.69 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | ALDH1A1 2125/4885HPGD 989/4885KDM4E 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.