Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.69 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.63 |
| ▸ | PPARG | P37231 | 5/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26074396 | 0.88 | RAB9A (1.00) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL3768739 | 0.81 | RAB9A (0.53) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL11918188 | 0.81 | NPC1 (0.79) | NPC1RAB9AATMSMN1; SMN2PTGES | |
| SCHEMBL7295509 | 0.81 | KCNK9 (0.80) | NPC1RAB9AALDH1A1KCNK9NR1H4 | |
| SCHEMBL22060020 | 0.81 | NR1H4 (0.84) | KCNK9NR1H4PPARGPPARAPPARD | |
| SCHEMBL7296261 | 0.80 | RAB9A (0.78) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL14195814 | 0.80 | KCNK9 (0.83) | NPC1RAB9AALDH1A1KCNK9NR1H4 | |
| SCHEMBL7294705 | 0.79 | MAPT (0.82) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL13762080 | 0.79 | KCNK9 (0.76) | NPC1RAB9AALDH1A1KCNK9NR1H4 | |
| SCHEMBL5223315 | 0.78 | RAB9A (0.73) | NPC1RAB9AALDH1A1GLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | NPC1 764/4885RAB9A 3256/4885ALDH1A1 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.