Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.82 |
| ▸ | HTT | P42858 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048773 | 0.86 | LMNA (0.79) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL30532978 | 0.86 | LMNA (0.79) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL14602130 | 0.84 | PKM (0.78) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL6795551 | 0.82 | LMNA (0.77) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL6037954 | 0.82 | LMNA (0.77) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL213547 | 0.82 | LMNA (0.77) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL399122 | 0.81 | LMNA (0.77) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6341219 | 0.80 | LMNA (0.79) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL7573915 | 0.79 | LMNA (0.78) | LMNAHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL10153812 | 0.79 | TSHR (0.61) | LMNAHTTSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | LMNA 4109/4885HTT 3785/4885SMN1; SMN2 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.