Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.61 |
| ▸ | HPGD | P15428 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003174 | 0.71 | ALDH1A1 (0.72) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL24290884 | 0.67 | NPC1 (0.66) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL20751769 | 0.67 | RAB9A (0.51) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL18868545 | 0.66 | — | — | |
| SCHEMBL5675393 | 0.64 | ADORA1 (1.00) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL24291380 | 0.62 | KMT2A (0.62) | ALDH1A1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL8277600 | 0.61 | AIP (0.62) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7003934 | 0.60 | ALDH1A1 (0.70) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL19435732 | 0.60 | NPC1 (0.51) | ALDH1A1HPGDRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL14610769 | 0.60 | NPC1 (0.73) | ALDH1A1HPGDRAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | ALDH1A1 2125/4885HPGD 989/4885RAB9A 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.