Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329953 | 0.86 | GAA (0.67) | KDM4EGAAALDH1A1L3MBTL1TSHR | |
| SCHEMBL5111331 | 0.80 | LMNA (0.62) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4548169 | 0.78 | SMN1; SMN2 (0.66) | KDM4EGAAALDH1A1L3MBTL1TSHR | |
| SCHEMBL6099753 | 0.77 | MAPT (0.56) | KDM4EGAAMAPK1ALDH1A1MEN1 | |
| SCHEMBL4498909 | 0.77 | POLB (0.53) | KDM4EGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1813423 | 0.77 | ALDH1A1 (1.00) | KDM4EGAAALDH1A1L3MBTL1TSHR | |
| SCHEMBL330021 | 0.77 | TMPRSS4 (0.69) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3496921 | 0.77 | TMPRSS4 (0.58) | KDM4EGAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL22778848 | 0.77 | MEN1 (0.69) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL13812897 | 0.77 | TMPRSS4 (0.65) | KDM4EGAAMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | KDM4E 3708/4885GAA 98/4885MAPK1 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.