Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208188 | 0.84 | MAPT (0.72) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL15797078 | 0.84 | MAPT (0.72) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL18711281 | 0.83 | MAPT (0.70) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL27918171 | 0.82 | MAPT (0.69) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL5236929 | 0.82 | MAPT (0.73) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL18375965 | 0.81 | RAB9A (0.79) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL631834 | 0.81 | MAPT (0.68) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL5543934 | 0.81 | MAPT (0.68) | MAPTSMN1; SMN2HTTMAPK1RAB9A | |
| SCHEMBL10144139 | 0.80 | MAPT (0.67) | MAPTSMN1; SMN2HTTMAPK1L3MBTL1 | |
| SCHEMBL626652 | 0.80 | HTR1A (0.67) | MAPTSMN1; SMN2HTTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPT 2982/4885SMN1; SMN2 4780/4885HTT 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.