Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144208 | 0.93 | TLR2 (0.40) | TLR2TPSAB1HDAC4MEF2DEP300 | |
| SCHEMBL10144210 | 0.92 | MDM2 (0.40) | TLR2TPSAB1HDAC4 | |
| SCHEMBL10144324 | 0.92 | TLR2 (0.44) | TLR2TPSAB1PTPN1HDAC4MEF2D | |
| SCHEMBL10144209 | 0.91 | TLR2 (0.39) | TLR2TPSAB1 | |
| SCHEMBL10144194 | 0.90 | MDM2 (0.39) | TLR2TPSAB1HDAC4 | |
| SCHEMBL10144413 | 0.84 | CA1 (0.40) | TLR2TPSAB1PTPN1HDAC4 | |
| SCHEMBL10143385 | 0.83 | MDM2 (0.38) | TLR2TPSAB1HDAC4KMT2A | |
| SCHEMBL10143383 | 0.83 | TLR2 (0.40) | TLR2TPSAB1 | |
| SCHEMBL10143518 | 0.82 | TLR2 (0.43) | TLR2TPSAB1PTPN1HDAC4MEF2D | |
| SCHEMBL10144446 | 0.82 | TLR2 (0.43) | TLR2TPSAB1PTPN1HDAC4MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |