Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144324 | 0.90 | TLR2 (0.44) | TLR2HDAC4MEF2DEP300TPSAB1 | |
| SCHEMBL10144130 | 0.89 | CA1 (0.39) | TLR2HDAC4TPSAB1MDM2 | |
| SCHEMBL10143518 | 0.89 | TLR2 (0.43) | TLR2HDAC4MEF2DEP300TPSAB1 | |
| SCHEMBL10143499 | 0.88 | TLR2 (0.45) | TLR2HDAC4MEF2DEP300TPSAB1 | |
| SCHEMBL10143502 | 0.86 | TLR2 (0.45) | TLR2HDAC4MEF2DEP300TPSAB1 | |
| SCHEMBL10143401 | 0.84 | TLR2 (0.46) | TLR2HDAC4PTPN1 | |
| SCHEMBL10143497 | 0.83 | TLR2 (0.42) | TLR2TPSAB1MDM2PTPN1 | |
| SCHEMBL10144428 | 0.83 | TLR2 (0.42) | TLR2HDAC4MEF2DEP300TPSAB1 | |
| SCHEMBL10143384 | 0.83 | TLR2 (0.37) | TLR2HDAC4MEF2DEP300TPSAB1 | |
| SCHEMBL10144426 | 0.83 | TLR2 (0.42) | TLR2HDAC4MEF2DTPSAB1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |