Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | USP2 | O75604 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26327805 | 0.81 | KMT2A (0.58) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL19403813 | 0.81 | SMN1; SMN2 (0.78) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL630705 | 0.79 | KMT2A (0.70) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL23252244 | 0.77 | POLB (0.56) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL22542070 | 0.77 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1TSHRMAPT | |
| SCHEMBL18067019 | 0.77 | TSHR (0.86) | KMT2AMEN1ALDH1A1TSHRMAPT | |
| SCHEMBL17884794 | 0.76 | KMT2A (0.70) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL26328340 | 0.76 | AR (0.69) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL26327879 | 0.76 | AR (0.69) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL26328366 | 0.76 | AR (0.69) | KMT2AUSP2MEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | KMT2A 1652/4885USP2 2359/4885MEN1 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.