SCHEMBL1014525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1014845	0.90	PDK2 (0.41)	HRH3PDK2PARP1KCNH2
	SCHEMBL13748292	0.90	HRH3 (0.43)	HRH3PDK2MEN1KMT2APARP1
	SCHEMBL1017656	0.89	HTT (0.39)	HRH3PDK2MEN1KMT2APARP1
	SCHEMBL1016129	0.88	ALDH1A1 (0.47)	HRH3PDK2KMT2ALMNAMAPT
	SCHEMBL1017564	0.86	HRH3 (0.39)	HRH3PDK2PLA2G7PARP1KCNH2
	SCHEMBL1014999	0.86	HRH3 (0.38)	HRH3KMT2APARP1KCNH2
	SCHEMBL13748340	0.83	CHRM2 (0.38)	HRH3PDK2MEN1KMT2APLA2G7
	SCHEMBL4061339	0.83	HRH3 (0.37)	HRH3PDK2PARP1KCNH2
	SCHEMBL13748854	0.83	SLC6A9 (0.43)	HRH3KMT2APARP1KCNH2
	SCHEMBL1018826	0.83	KDM4E (0.39)	HRH3PARP1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.