Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TACR3 | P29371 | 8/20 | 0.46 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013614 | 0.94 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB | |
| SCHEMBL1069117 | 0.94 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB | |
| SCHEMBL1013638 | 0.94 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB | |
| SCHEMBL1012675 | 0.93 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB | |
| SCHEMBL14076822 | 0.86 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB | |
| SCHEMBL5107752 | 0.83 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL13223061 | 0.83 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL5104795 | 0.83 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL3049441 | 0.82 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB | |
| SCHEMBL3053198 | 0.81 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1TACR3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272858-A2 | HCV inhibitors comprising beta amino acids and their uses | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |
| US-20080045530-A1 | Organic Compounds and Their Uses | BRANDL TRIXI | 2008-02-21 | — | — | US | disclosed |
| US-20080045530-A1 | Organic Compounds and Their Uses | BRANDL TRIXI | 2008-02-21 | — | — | US | disclosed |
| US-20080045530-A1 | Organic Compounds and Their Uses | BRANDL TRIXI | 2008-02-21 | — | — | US | disclosed |
| WO-2007121124-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045530-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | KDM4E 4021/4885SMN1; SMN2 877/4885ALDH1A1 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.