Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145459 | 0.87 | FTO (0.51) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL5936701 | 0.86 | MAPT (0.69) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL10145452 | 0.85 | MAPT (0.54) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL16018455 | 0.85 | MAPT (0.61) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL10145462 | 0.84 | CYP3A4 (0.51) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL12796936 | 0.84 | FTO (0.57) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL12152351 | 0.83 | MAPT (0.63) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL10347954 | 0.83 | MAPT (0.66) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL29417941 | 0.83 | MAPT (0.66) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL10145450 | 0.80 | MAPT (0.58) | MAPTFTOMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |