Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347954 | 0.97 | MAPT (0.66) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL29417941 | 0.97 | MAPT (0.66) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL12152351 | 0.94 | MAPT (0.63) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL16018455 | 0.93 | MAPT (0.61) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL14415063 | 0.92 | FTO (0.60) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL12863674 | 0.92 | FTO (0.85) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL26472361 | 0.91 | MAPT (0.59) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL12796936 | 0.90 | FTO (0.57) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL18363816 | 0.90 | CYP3A4 (0.67) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL12929974 | 0.90 | MAPT (0.57) | MAPTFTOMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018133859-A1 | COMPOUNDS AND METHODS FOR DETECTION OF HYDROGEN PEROXIDE | THE UNIVERSITY OF HONG KONG (CN) | 2018-07-26 | — | — | WO | disclosed |
| US-20180036312-A1 | Novel Scaffolds for Intracellular Compound Delivery for the Detection of Cancer Cells | ISI LIFE SCIENCES INC (US) | 2018-02-08 | — | — | US | disclosed |
| US-9637773-B2 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties | ENZO LIFE SCIENCES, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-9637773-B2 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties | ENZO LIFE SCIENCES, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-20170044593-A1 | PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2017-02-16 | — | — | US | disclosed |
| US-9528990-B2 | Fluorogenic/fluorescent probes derivative from sulfoxanthene, and use thereof | BIOMERIEUX S.A. (FR) | 2016-12-27 | — | — | US | disclosed |
| US-20160146814-A1 | Fluorogenic/Fluorescent Probes Derivative from Sulfoxanthene, and Use Thereof | INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE ROUEN (FR) | 2016-05-26 | — | — | US | disclosed |
| US-9212189-B2 | Fluorescent probes for reactive sulfur species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120107725-A1 | Solid Polymer Electrolyte Composition, and Ion-Exchange Membrane, Membrane Electrode Assembly and Fuel Cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20070172861-A1 | Mutant polymerases | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172866-A1 | Methods for sequence determination using depolymerizing agent | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172862-A1 | Data stream determination | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172868-A1 | Compositions for sequence determination using tagged polymerizing agents and tagged monomers | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172863-A1 | Compositions and methods for sequence determination | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172865-A1 | Sequence determination in confined regions | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172867-A1 | Methods for sequence determination | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172864-A1 | Composition for sequence determination | GAO XIAOLIAN | 2007-07-26 | — | — | US | disclosed |
| US-20070172858-A1 | Methods for sequence determination | HARDIN SUSAN | 2007-07-26 | — | — | US | disclosed |
| US-7195884-B2 | Methods and kits for transferases | PROMEGA CORP. (US) | 2007-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070172861-A1 | Mutant polymerases | POLM, POLRMT, RNGTT | MAPT 3002/4885FTO 3580/4885MEN1 4317/4885 |
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | SQOR, CBS, CTH | MAPT 3936/4885FTO 3276/4885MEN1 3197/4885 |
| US-20180036312-A1 | Novel Scaffolds for Intracellular Compound Delivery for the Detection of Cancer Cells | MTHFD1, DHFR, FOLR1 | MAPT 3243/4885FTO 1275/4885MEN1 2724/4885 |
| US-20070172864-A1 | Composition for sequence determination | RNGTT, POLRMT, POLM | MAPT 2446/4885FTO 2335/4885MEN1 3756/4885 |
| US-20170044593-A1 | PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA | DPEP1, MRPL21, RCE1 | MAPT 4329/4885FTO 3815/4885MEN1 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.