Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848641 | 0.79 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20079201 | 0.70 | SLC6A4 (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL25530516 | 0.70 | SLC6A4 (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL24920427 | 0.70 | NPSR1 (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL422018 | 0.67 | — | — | |
| SCHEMBL419801 | 0.66 | DPP4 (0.34) | — | |
| SCHEMBL421003 | 0.66 | DPP4 (0.34) | — | |
| SCHEMBL420711 | 0.66 | DPP4 (0.34) | — | |
| SCHEMBL26514351 | 0.65 | HTR3E (0.32) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20038122 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415765-A1 | PYRIMIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |