Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 5/20 | 0.37 |
| ▸ | TOP1 | P11387 | 4/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CYCS | P99999 | 4/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336198 | 0.91 | STAT3 (0.51) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL3286041 | 0.84 | STAT3 (0.64) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL30519987 | 0.84 | STAT3 (0.64) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL8689820 | 0.84 | STAT3 (0.68) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL30574153 | 0.83 | STAT3 (0.66) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL30205816 | 0.82 | STAT3 (0.64) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL5319095 | 0.82 | STAT3 (0.64) | STAT3STAT1TERTTOP1ABCG2 | |
| Iodide SCHEMBL27581324 | 0.81 | STAT3 (0.63) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL336446 | 0.80 | STAT3 (0.39) | STAT3STAT1TOP1ABCG2CYCS | |
| SCHEMBL17972795 | 0.79 | STAT3 (0.57) | STAT3STAT1TERTTOP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140106367-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140106367-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-8530459-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-8530459-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | disclosed |
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | disclosed |
| US-8097609-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-17 | — | — | US | disclosed |
| US-8097609-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090297456-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-03 | — | — | US | disclosed |
| US-20090297456-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | ALK, ACVRL1, ACVR1 | STAT3 2034/4885STAT1 2300/4885TERT 2022/4885 |
| US-20090297456-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | ALK, ACVRL1, ACVR1 | STAT3 1926/4885STAT1 2247/4885TERT 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.