SCHEMBL3286041

SCHEMBL3286041

Cc1ccc(-c2c3nc(c(-c4ccc(C)cc4)c4ccc([nH]4)c(-c4ccc(C)cc4)c4nc(cc5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.64
▸ STAT1 P42224 1/20 0.64
▸ TERT O14746 6/20 0.48
▸ TOP1 P11387 4/20 0.47
▸ CYCS P99999 3/20 0.46
▸ ABCG2 Q9UNQ0 1/20 0.45
▸ ENPP2 Q13822 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30519987 1.00 STAT3 (0.64) STAT3STAT1TERTTOP1CYCS
SCHEMBL8689820 0.97 STAT3 (0.68) STAT3STAT1TERTTOP1CYCS
SCHEMBL30574153 0.96 STAT3 (0.66) STAT3STAT1TERTTOP1CYCS
SCHEMBL30205816 0.94 STAT3 (0.64) STAT3STAT1TERTTOP1CYCS
SCHEMBL5319095 0.94 STAT3 (0.64) STAT3STAT1TERTTOP1CYCS
SCHEMBL10100939 0.94 STAT3 (0.57) STAT3STAT1TERTTOP1CYCS
Iodide SCHEMBL27581324 0.93 STAT3 (0.63) STAT3STAT1TERTTOP1CYCS
SCHEMBL93007 0.93 STAT3 (0.56) STAT3STAT1TERTTOP1CYCS
SCHEMBL17972795 0.89 STAT3 (0.57) STAT3STAT1TERTTOP1CYCS
SCHEMBL10100937 0.89 STAT3 (0.52) STAT3STAT1TERTTOP1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718794-B2 Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers NORTH CAROLINA STATE UNIVERSITY (US) 2010-05-18 — — US disclosed
US-20080194839-A1 SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS NORTH CAROLINA STATE UNIVERSITY (US) 2008-08-14 — — US disclosed
US-7378520-B2 Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers NORTH CAROLINA STATE UNIVERSITY (US) 2008-05-27 — — US disclosed
EP-1763317-A1 SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS North Carolina State University (US) 2007-03-21 — — EP disclosed
WO-2006016943-A1 SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS NORTH CAROLINA STATE UNIVERSITY (US) 2006-02-16 — — WO disclosed
US-20060009638-A1 Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers ZETTACORE, INC. 2006-01-12 — — US disclosed
EP-0367326-B1 Process for preparing a cycloalkanone and/or cycloalkanol DSM NV (NL) 1993-12-29 — — EP disclosed
EP-0453021-A1 Process for preparing a cycloalkanone and/or cycloalkanol DSM N.V. (NL) 1991-10-23 — — EP disclosed
US-5004837-A Oxidation of cycloalkane STAMICARBON B.V. (NL) 1991-04-02 — — US disclosed
EP-0367326-A1 Process for preparing a cycloalkanone and/or cycloalkanol DSM N.V. (NL) 1990-05-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009638-A1 Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers SCO2, PPOX, HCCS STAT3 3903/4885STAT1 4663/4885TERT 2371/4885
US-20080194839-A1 SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS SCO2, PPOX, HCCS STAT3 3903/4885STAT1 4663/4885TERT 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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