Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 17/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147216 | 0.87 | DGAT1 (0.65) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL10146443 | 0.84 | DGAT1 (0.87) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL5786275 | 0.81 | NPY5R (0.85) | NPY5R | |
| SCHEMBL10146489 | 0.75 | DGAT1 (0.88) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL10146480 | 0.75 | DGAT1 (0.77) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL4789172 | 0.73 | NPY5R (0.85) | NPY5R | |
| SCHEMBL10147136 | 0.73 | DGAT1 (0.73) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL10146482 | 0.72 | DGAT1 (0.88) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL10146550 | 0.72 | DGAT1 (0.69) | DGAT1NPY5RCYP2C9 | |
| SCHEMBL4789175 | 0.72 | NPY5R (1.00) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009217-A1 | SPIROCYCLIC COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-01-19 | — | — | WO | disclosed |