Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853160 | 0.87 | HTR2C (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL26036401 | 0.87 | HTR2C (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL1853162 | 0.87 | HTR2C (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL1014494 | 0.87 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL17407822 | 0.85 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL22820268 | 0.85 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL28595566 | 0.85 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL28585122 | 0.85 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL17016835 | 0.84 | HTR2A (0.35) | HTR2AHTR2CHTR2BRIPK1BRD4 | |
| SCHEMBL15445798 | 0.84 | RIPK1 (0.41) | HTR2AHTR2CHTR2BRIPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272837-B1 | LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2014-12-17 | — | — | EP | disclosed |
| EP-2272837-A1 | LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | Chisso Corporation (JP) | 2011-01-12 | — | — | EP | disclosed |