Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 6/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147510 | 0.88 | BRD4 (0.53) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10146103 | 0.77 | BRD4 (0.55) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL352017 | 0.77 | CNR2 (0.52) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13618718 | 0.74 | BRD4 (0.51) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10147542 | 0.72 | MAPK13 (0.37) | CNR2MAPT | |
| SCHEMBL19625484 | 0.70 | MEN1 (0.69) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20291059 | 0.69 | BRD4 (1.00) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20291195 | 0.67 | BRD4 (0.50) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10147579 | 0.67 | NPC1 (0.33) | BRD4NPC1RAB9A | |
| SCHEMBL352100 | 0.65 | BRD4 (0.48) | BRD4MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |