Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147494 | 0.81 | CNR2 (0.30) | NPC1RAB9A | |
| SCHEMBL10147510 | 0.79 | BRD4 (0.53) | NPC1RAB9ABRD4MAPK14 | |
| SCHEMBL352888 | 0.78 | MAOA (0.36) | MAPK14 | |
| SCHEMBL10146116 | 0.77 | CYP1A2 (0.37) | MAPK14 | |
| SCHEMBL10147588 | 0.77 | CYP1A2 (0.33) | NPC1RAB9AMAPK14 | |
| SCHEMBL10147805 | 0.75 | — | — | |
| SCHEMBL10147582 | 0.74 | — | — | |
| SCHEMBL351653 | 0.74 | HDAC1 (0.33) | NPC1RAB9AMAPK14 | |
| SCHEMBL13618545 | 0.74 | ALDH1A1 (0.32) | MAPK14 | |
| SCHEMBL12245198 | 0.70 | PTGS2 (0.48) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |