Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722736 | 0.82 | MEN1 (0.63) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL21300548 | 0.78 | MAOB (0.64) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL20203126 | 0.77 | MEN1 (0.52) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL8385525 | 0.77 | MEN1 (0.59) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL12085703 | 0.76 | MEN1 (0.52) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL15268088 | 0.75 | MEN1 (0.54) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL18850173 | 0.73 | ESR1 (0.52) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL22683261 | 0.73 | MEN1 (0.46) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL339126 | 0.73 | MEN1 (0.65) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL8272631 | 0.73 | MAOB (0.69) | MEN1NPC1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | MEN1 3501/4885NPC1 4164/4885ALDH1A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.