Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.64 |
| ▸ | MAOA | P21397 | 13/20 | 0.64 |
| ▸ | PRKCI | P41743 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222772 | 0.92 | MAOB (0.69) | MAOBMAOAHRH3 | |
| SCHEMBL14382308 | 0.88 | MAOB (0.65) | MAOBMAOAHRH3 | |
| SCHEMBL6825904 | 0.86 | MAOB (0.67) | MAOBMAOAHRH3 | |
| SCHEMBL8272631 | 0.83 | MAOB (0.69) | MAOBMAOAMEN1NPC1ALDH1A1 | |
| SCHEMBL722736 | 0.83 | MEN1 (0.63) | MAOBMEN1NPC1ALDH1A1GAA | |
| SCHEMBL21297626 | 0.81 | MAOB (0.88) | MAOBMAOAPRKCINPC1ALDH1A1 | |
| SCHEMBL1377016 | 0.81 | MAOB (0.69) | MAOBMAOAHRH3 | |
| SCHEMBL27974960 | 0.81 | MAOB (0.66) | MAOBMAOAMEN1NPC1ALDH1A1 | |
| SCHEMBL6825249 | 0.81 | MAOB (0.66) | MAOBMAOAHRH3 | |
| SCHEMBL228128 | 0.80 | MAOA (1.00) | MAOBMAOAPRKCIMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019163917-A1 | COMPOUND HAVING S1P5 RECEPTOR AGONIST ACTIVITY | 小野薬品工業株式会社 | 2019-08-29 | — | — | WO | disclosed |