Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721338 | 0.92 | MEN1 (0.52) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL14878532 | 0.86 | THRA (0.51) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL12083159 | 0.85 | THRA (0.47) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL21300548 | 0.83 | MAOB (0.64) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL3316098 | 0.82 | THRA (0.45) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL10147575 | 0.82 | MEN1 (0.56) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL15268088 | 0.80 | MEN1 (0.54) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL23142696 | 0.80 | MAOB (0.58) | MIFMAOBAKR1B1 | |
| SCHEMBL23158881 | 0.79 | ITGB3 (0.55) | MAOBHRH3 | |
| SCHEMBL8272631 | 0.79 | MAOB (0.69) | MEN1NPC1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293719-A1 | PEPTIDE-LIPOSOME COMPLEX FOR MULTIVALENT CROSSLINKING WITH PD-L1 AND COMPOSITION INCLUDING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-09-21 | — | — | US | disclosed |
| US-9801943-B2 | Method for in vivo targeting of nanoparticles via bioorthogonal copper-free click chemistry | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-10-31 | — | — | US | disclosed |
| US-9801943-B2 | Method for in vivo targeting of nanoparticles via bioorthogonal copper-free click chemistry | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-10-31 | — | — | US | disclosed |
| US-20130251784-A1 | METHOD FOR IN VIVO TARGETING OF NANOPARTICLES VIA BIOORTHOGONAL COPPER-FREE CLICK CHEMISTRY | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-09-26 | — | — | US | disclosed |
| US-20130251784-A1 | METHOD FOR IN VIVO TARGETING OF NANOPARTICLES VIA BIOORTHOGONAL COPPER-FREE CLICK CHEMISTRY | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-09-26 | — | — | US | disclosed |
| US-8541625-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-8541625-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-8426649-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426649-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120295318-A1 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295318-A1 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | WEE1, WEE2, MPI | MEN1 3501/4885NPC1 4164/4885ALDH1A1 205/4885 |
| US-20130251784-A1 | METHOD FOR IN VIVO TARGETING OF NANOPARTICLES VIA BIOORTHOGONAL COPPER-FREE CLICK CHEMISTRY | AOC3, AOC1, DDO | MEN1 977/4885NPC1 565/4885ALDH1A1 54/4885 |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | WEE1, WEE2, MPI | MEN1 3501/4885NPC1 4164/4885ALDH1A1 205/4885 |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | MEN1 3501/4885NPC1 4164/4885ALDH1A1 205/4885 |
| US-20230293719-A1 | PEPTIDE-LIPOSOME COMPLEX FOR MULTIVALENT CROSSLINKING WITH PD-L1 AND COMPOSITION INCLUDING THE SAME | PDCD1LG2, CD274, PDCD1 | MEN1 342/4885NPC1 2053/4885ALDH1A1 4308/4885 |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | MEN1 3501/4885NPC1 4164/4885ALDH1A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.