Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352485 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPTMAPK1NPSR1CYP1A2 | |
| SCHEMBL10147582 | 0.79 | — | — | |
| SCHEMBL351008 | 0.77 | CNR2 (0.39) | CYP1A2RAB9A | |
| SCHEMBL10147588 | 0.75 | CYP1A2 (0.33) | CYP1A2RAB9A | |
| SCHEMBL10146105 | 0.74 | CYP1A2 (0.44) | CYP1A2 | |
| SCHEMBL13618724 | 0.71 | GRN (0.40) | CYP1A2 | |
| SCHEMBL350907 | 0.66 | CNR2 (0.51) | ALDH1A1MAPTRAB9A | |
| SCHEMBL10147542 | 0.65 | MAPK13 (0.37) | MAPT | |
| SCHEMBL350932 | 0.61 | ALDH1A1 (0.35) | ALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL351826 | 0.61 | CNR2 (0.36) | ALDH1A1NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |