Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146105 | 0.89 | CYP1A2 (0.44) | GRNSORT1KDM4ECYP1A2HDAC6 | |
| SCHEMBL13618555 | 0.75 | KDM4E (0.36) | GRNSORT1KDM4E | |
| SCHEMBL10147588 | 0.75 | CYP1A2 (0.33) | GRNSORT1KDM4ECYP1A2 | |
| SCHEMBL10147542 | 0.75 | MAPK13 (0.37) | — | |
| SCHEMBL350907 | 0.74 | CNR2 (0.51) | GRNSORT1KDM4E | |
| SCHEMBL13618717 | 0.72 | KDM4E (0.36) | GRNSORT1KDM4E | |
| SCHEMBL13618548 | 0.72 | KDM4E (0.36) | GRNSORT1KDM4E | |
| SCHEMBL10147580 | 0.71 | ALDH1A1 (0.33) | CYP1A2 | |
| SCHEMBL352485 | 0.71 | ALDH1A1 (0.35) | GRNSORT1KDM4ECYP1A2 | |
| SCHEMBL13618545 | 0.70 | ALDH1A1 (0.32) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |