Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890085 | 0.85 | TSHR (0.35) | TSHRCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL11400831 | 0.76 | CCNB2 (0.51) | TSHRCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL24323747 | 0.74 | ALDH1A1 (0.42) | TSHRCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL30588641 | 0.74 | ALDH1A1 (0.42) | TSHRCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL26126507 | 0.74 | IKBKB (0.33) | IKBKBCHUKTSHRCCNB2CDK1 | |
| SCHEMBL10147095 | 0.72 | BRD4 (0.35) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL26124614 | 0.71 | TSHR (0.35) | TSHRCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL12938133 | 0.70 | TSHR (0.36) | TSHR | |
| SCHEMBL12437101 | 0.69 | CCNB2 (0.37) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL25093856 | 0.69 | PARP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | NSUN2, HCCS, HAVCR2 | IKBKB 396/4885CHUK 320/4885TSHR 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.