Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890085 | 0.82 | TSHR (0.35) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL13122872 | 0.81 | CCNB2 (0.32) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL10147095 | 0.78 | BRD4 (0.35) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL13154922 | 0.77 | CCNB2 (0.57) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL25093856 | 0.74 | PARP1 (0.36) | — | |
| SCHEMBL31526668 | 0.74 | CDK5 (0.44) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL21885846 | 0.74 | ALDH1A1 (0.50) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL17090692 | 0.71 | ADORA2A (0.38) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL18238553 | 0.70 | RPS6KA3 (0.38) | CDK1CDK5 | |
| SCHEMBL12965805 | 0.70 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, HCCS, NSUN2 | CCNB2 189/4885CDK1 484/4885CCNB1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.