Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724964 | 0.83 | CYP2D6 (0.34) | MAPTALDH1A1TSHRABCB1 | |
| SCHEMBL6982991 | 0.83 | CYP2D6 (0.34) | MAPTALDH1A1TSHRABCB1 | |
| SCHEMBL339167 | 0.83 | CYP2D6 (0.34) | MAPTALDH1A1TSHRABCB1 | |
| SCHEMBL10147734 | 0.82 | MAPT (0.36) | MAPTALDH1A1TSHRABCB1CYP2C9 | |
| SCHEMBL6973352 | 0.76 | — | — | |
| SCHEMBL10147723 | 0.71 | ALDH1A1 (0.32) | MAPTALDH1A1TSHR | |
| SCHEMBL28813457 | 0.70 | CYP2D6 (0.33) | TSHR | |
| SCHEMBL13766891 | 0.69 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL14724963 | 0.68 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15468432 | 0.68 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |