Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972448 | 0.83 | — | — | |
| SCHEMBL10147734 | 0.73 | MAPT (0.36) | ALDH1A1MAPTTSHR | |
| SCHEMBL10147753 | 0.71 | MAPT (0.34) | ALDH1A1MAPTTSHR | |
| SCHEMBL12112084 | 0.68 | — | — | |
| SCHEMBL10147719 | 0.67 | MAPT (0.42) | ALDH1A1MAPTTSHR | |
| SCHEMBL10147759 | 0.67 | THRB (0.49) | ALDH1A1MAPTTSHR | |
| SCHEMBL10147765 | 0.67 | THRB (0.49) | ALDH1A1MAPTTSHR | |
| SCHEMBL10147766 | 0.66 | ALDH1A1 (0.36) | ALDH1A1MAPTTSHR | |
| SCHEMBL10147769 | 0.61 | THRB (0.55) | ALDH1A1MAPTTSHR | |
| SCHEMBL10147732 | 0.61 | CYP2D6 (0.36) | ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |