Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350606 | 0.89 | CNR2 (0.49) | CNR2CNR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL10147480 | 0.76 | MEN1 (0.37) | CNR2CNR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL10146065 | 0.74 | MEN1 (0.49) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1252445 | 0.74 | CNR2 (0.41) | CNR2CNR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL13618544 | 0.70 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2HTTNPC1 | |
| SCHEMBL352017 | 0.69 | CNR2 (0.52) | CNR2CNR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL19625484 | 0.67 | MEN1 (0.69) | CNR2CNR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL10177216 | 0.63 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2HTTNPC1 | |
| SCHEMBL15121174 | 0.61 | CNR2 (0.63) | CNR2CNR1ALDH1A1MAPK1MEN1 | |
| SCHEMBL19625366 | 0.61 | LTA4H (0.47) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |