Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146065 | 0.89 | MEN1 (0.49) | MEN1KMT2ARETBRD4EGFR | |
| SCHEMBL10177216 | 0.75 | MEN1 (0.45) | MEN1KMT2ARETBRD4EGFR | |
| SCHEMBL350606 | 0.72 | CNR2 (0.49) | MEN1KMT2ABRD4NPC1RAB9A | |
| SCHEMBL10147480 | 0.72 | MEN1 (0.37) | MEN1KMT2ABRD4HTT | |
| SCHEMBL13618718 | 0.72 | BRD4 (0.51) | MEN1KMT2ARETBRD4EGFR | |
| SCHEMBL10147809 | 0.70 | CNR2 (0.43) | MEN1KMT2ABRD4NPC1RAB9A | |
| SCHEMBL13618564 | 0.65 | MEN1 (0.44) | MEN1KMT2ARETBRD4EGFR | |
| SCHEMBL10243416 | 0.65 | MEN1 (0.56) | MEN1KMT2ARETBRD4EGFR | |
| SCHEMBL799923 | 0.62 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL10146103 | 0.62 | BRD4 (0.55) | MEN1KMT2ARETBRD4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |