SCHEMBL1014819

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1017219	0.99	ALDH1A1 (0.48)	ALDH1A1KMT2ATSHRACHEHRH3
	SCHEMBL1019868	0.93	ALDH1A1 (0.42)	ALDH1A1KMT2ATSHRACHERAB9A
	SCHEMBL1603788	0.91	NPC1 (0.45)	ALDH1A1KMT2ATSHRACHERAB9A
	SCHEMBL1603700	0.89	RAB9A (0.46)	ALDH1A1KMT2AHRH3RAB9ANPC1
	SCHEMBL1013716	0.89	MAPK1 (0.46)	ALDH1A1KMT2ATSHRHRH3RAB9A
	SCHEMBL1015009	0.89	NPC1 (0.46)	ALDH1A1KMT2ATSHRACHERAB9A
	SCHEMBL1017073	0.89	RAB9A (0.43)	ALDH1A1KMT2ATSHRHRH3RAB9A
	SCHEMBL1603677	0.89	RAB9A (0.47)	ALDH1A1KMT2AACHEHRH3RAB9A
	SCHEMBL1017049	0.89	RAB9A (0.48)	ALDH1A1KMT2ATSHRHRH3RAB9A
	SCHEMBL1017736	0.88	TSHR (0.46)	ALDH1A1KMT2ATSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.