SCHEMBL10148982

SCHEMBL10148982

CO[C@H]1OC(COS(=O)(=O)O)[C@@H](O[C@@H]2OC(C(=O)O)[C@H](O[C@@H]3OC(COS(=O)(=O)O)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](O[C@H]5OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C5N)[C@H](O)C4O)[C@@H](OSOOO)C3N)[C@@H](O)C2OS(=O)(=O)O)[C@H](O)C1N

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 7/20 0.62
SERPINC1 P01008 3/20 0.47
FGF1 P05230 4/20 0.42
BDNF P23560 3/20 0.40
PTN P21246 2/20 0.40
MDK P21741 2/20 0.40
CXCL10 P02778 1/20 0.39
CXCL8 P10145 1/20 0.39
CCL2 P13500 1/20 0.39
CCL5 P13501 1/20 0.39
CXCL12 P48061 1/20 0.39
F2 P00734 1/20 0.36
FGF2 P09038 2/20 0.34
HPSE Q9Y251 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13796405 1.00 F10 (0.62) F10SERPINC1FGF1BDNFPTN
SCHEMBL15171284 0.91 F10 (0.69) F10SERPINC1FGF1BDNFPTN
SCHEMBL14817755 0.91 F10 (0.69) F10SERPINC1FGF1BDNFPTN
SCHEMBL19619414 0.91 F10 (0.69) F10SERPINC1FGF1BDNFPTN
SCHEMBL15296510 0.88 F10 (0.65) F10SERPINC1FGF1BDNFPTN
SCHEMBL15171262 0.88 F10 (0.65) F10SERPINC1FGF1BDNFPTN
SCHEMBL27433034 0.85 F10 (0.61) F10SERPINC1FGF1BDNFPTN
SCHEMBL13795898 0.84 F10 (0.85) F10SERPINC1FGF1BDNFPTN
SCHEMBL10148985 0.84 F10 (0.85) F10SERPINC1FGF1BDNFPTN
SCHEMBL16418343 0.81 F10 (0.58) F10SERPINC1FGF1BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114970-B2 Synthetic heparin monosaccharides ALCHEMIA LIMITED (AU) 2012-02-14 US disclosed
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES ALCHEMIA LIMITED (AU) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES HPSE, DDOST, STT3A F10 107/4885SERPINC1 8/4885FGF1 195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.