SCHEMBL13796405

CO[C@H]1OC(COS(=O)(=O)O)[C@@H](O[C@@H]2OC(C(=O)O)[C@@H](O[C@@H]3OC(COS(=O)(=O)O)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](O[C@H]5OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C5N)[C@H](O)C4O)C(OSOOO)[C@@H]3N)[C@@H](O)C2OS(=O)(=O)O)C(O)[C@@H]1N

nearest known ligand 0.62

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	7/20	0.62

▸	SERPINC1	P01008	3/20	0.47

▸	FGF1	P05230	4/20	0.42

▸	BDNF	P23560	3/20	0.40

▸	PTN	P21246	2/20	0.40

▸	MDK	P21741	2/20	0.40

▸	CXCL10	P02778	1/20	0.39

▸	CXCL8	P10145	1/20	0.39

▸	CCL2	P13500	1/20	0.39

▸	CCL5	P13501	1/20	0.39

▸	CXCL12	P48061	1/20	0.39

▸	F2	P00734	1/20	0.36

▸	FGF2	P09038	2/20	0.34

▸	HPSE	Q9Y251	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10148982	1.00	F10 (0.62)	F10SERPINC1FGF1BDNFPTN
SCHEMBL15171284	0.91	F10 (0.69)	F10SERPINC1FGF1BDNFPTN
SCHEMBL14817755	0.91	F10 (0.69)	F10SERPINC1FGF1BDNFPTN
SCHEMBL19619414	0.91	F10 (0.69)	F10SERPINC1FGF1BDNFPTN
SCHEMBL15171262	0.88	F10 (0.65)	F10SERPINC1FGF1BDNFPTN
SCHEMBL15296510	0.88	F10 (0.65)	F10SERPINC1FGF1BDNFPTN
SCHEMBL27433034	0.85	F10 (0.61)	F10SERPINC1FGF1BDNFPTN
SCHEMBL13795898	0.84	F10 (0.85)	F10SERPINC1FGF1BDNFPTN
SCHEMBL10148985	0.84	F10 (0.85)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16418343	0.81	F10 (0.58)	F10SERPINC1FGF1BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7541445-B2	Synthetic heparin pentasaccharides	ALCHEMIA LIMITED (AU)	2009-06-02	—	—	US	disclosed