SCHEMBL10149699

SCHEMBL10149699

Cc1ccc2c3ccccc3n(-c3ccccc3-c3ccccc3-c3nnc4c5ccccc5c5ccccc5n34)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.41
PDE2A O00408 11/20 0.34
PDE10A Q9Y233 10/20 0.34
MAPT P10636 4/20 0.34
TP53 P04637 3/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10127703 0.90 POLB (0.44) POLBPDE2APDE10ATP53TUBB4A
SCHEMBL10127685 0.85 POLB (0.46) POLBPDE2APDE10ATP53TUBB4A
SCHEMBL26481413 0.82 ALDH1A1 (0.41) POLBMAPTLMNATDO2IDO2
SCHEMBL26340818 0.82 ALDH1A1 (0.41) POLBMAPTLMNATDO2IDO2
SCHEMBL10127701 0.80 POLB (0.48) POLBMAPTTP53LMNARXFP1
SCHEMBL10127690 0.80 POLB (0.47) POLBPDE2APDE10AMAPTTP53
SCHEMBL10127724 0.77 POLB (0.48) POLBMAPTTP53RXFP1
SCHEMBL23423816 0.77 L3MBTL1 (0.42) MAPTLMNATDO2IDO2
SCHEMBL10127714 0.77 POLB (0.44) POLBPDE2APDE10AMAPTTUBB4A
SCHEMBL10127686 0.76 POLB (0.45) POLBPDE2APDE10AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012017842-A1 TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 WO disclosed