Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12299205 | 0.78 | TSHR (0.34) | HPGDTSHR | |
| SCHEMBL13456486 | 0.77 | — | — | |
| SCHEMBL15233491 | 0.77 | — | — | |
| SCHEMBL13642688 | 0.77 | — | — | |
| SCHEMBL10150735 | 0.77 | TSHR (0.37) | HPGDTSHR | |
| SCHEMBL10107898 | 0.77 | TSHR (0.37) | HPGDTSHR | |
| SCHEMBL1357811 | 0.74 | TSHR (0.38) | HPGDTSHR | |
| SCHEMBL16309384 | 0.73 | HPGD (0.33) | HPGDTSHR | |
| SCHEMBL15861024 | 0.72 | HPGD (0.36) | HPGDTSHR | |
| SCHEMBL13497244 | 0.70 | LPAR1 (0.34) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044498-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2010132759-A9 | ANTIBACTERIAL DERIVATIVES OF DIBEKACIN | ACHAOGEN, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011044498-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |