Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497244 | 0.83 | LPAR1 (0.34) | TSHRHPGD | |
| SCHEMBL13226053 | 0.80 | ALDH1A1 (0.34) | TSHRHPGDALDH1A1 | |
| SCHEMBL10149912 | 0.78 | HPGD (0.33) | TSHRHPGD | |
| SCHEMBL10107898 | 0.78 | TSHR (0.37) | TSHRHPGDALDH1A1 | |
| SCHEMBL10150735 | 0.78 | TSHR (0.37) | TSHRHPGDALDH1A1 | |
| SCHEMBL15861024 | 0.77 | HPGD (0.36) | TSHRHPGDALDH1A1 | |
| SCHEMBL13642224 | 0.77 | — | — | |
| SCHEMBL13456635 | 0.77 | — | — | |
| SCHEMBL1357811 | 0.76 | TSHR (0.38) | TSHRHPGDDNM1ALDH1A1ADRB2 | |
| SCHEMBL15003145 | 0.76 | TSHR (0.35) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132759-A9 | ANTIBACTERIAL DERIVATIVES OF DIBEKACIN | ACHAOGEN, INC. (US) | 2011-09-09 | — | — | WO | disclosed |