Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10150735 | 1.00 | TSHR (0.37) | TSHRHPGDATMALDH1A1CNR1 | |
| SCHEMBL1357811 | 0.82 | TSHR (0.38) | TSHRHPGDATMALDH1A1CNR1 | |
| SCHEMBL28354055 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CNR1CNR2CYP3A4 | |
| SCHEMBL15861024 | 0.79 | HPGD (0.36) | TSHRHPGDATMALDH1A1CNR1 | |
| SCHEMBL12299205 | 0.78 | TSHR (0.34) | TSHRHPGDALDH1A1 | |
| SCHEMBL13642260 | 0.77 | SGPL1 (0.30) | TSHRHPGD | |
| SCHEMBL13456484 | 0.77 | SGPL1 (0.30) | TSHRHPGD | |
| SCHEMBL13644235 | 0.77 | SGPL1 (0.30) | TSHRHPGD | |
| SCHEMBL10149912 | 0.77 | HPGD (0.33) | TSHRHPGD | |
| SCHEMBL15003146 | 0.76 | HPGD (0.32) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044502-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2010132757-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011044502-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |