Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015021 | 1.00 | MEN1 (0.50) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL8847188 | 0.83 | MEN1 (0.47) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL14738587 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL3659496 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL8546431 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL2021797 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL31132874 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL4881052 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL21979547 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1ALOX15CYP1A2 | |
| SCHEMBL7278987 | 0.77 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX15AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271346-B1 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2271346-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009120652-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| CN-1042899-C | Catalyst compositions and Catalytic processes | PHILLIPS PETROLEUM CO (US) | 1999-04-14 | — | — | CN | disclosed |
| EP-0603557-B1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM CO (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5461126-A | Process of polymerizing olefins using organonickel catalyst compositions | PHILLIPS PETROLEUM COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| CN-1091999-A | Carbon monoxide-olefin polymeric and Catalytic processes | PHILLIPS PETROLEUM CO (US) | 1994-09-14 | — | — | CN | disclosed |
| US-5332708-A | Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0603557-A1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |