Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HNF4A | P41235 | 3/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636683 | 0.77 | DHODH (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2ACMSD | |
| SCHEMBL1015022 | 0.77 | MEN1 (0.50) | MEN1KMT2AALDH1A1ALOX15AKR1C3 | |
| SCHEMBL1015021 | 0.77 | MEN1 (0.50) | MEN1KMT2AALDH1A1ALOX15AKR1C3 | |
| SCHEMBL10633622 | 0.75 | SERPINE1 (0.46) | MEN1KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL8847188 | 0.73 | MEN1 (0.47) | MEN1KMT2AHNF4APTPN1ALDH1A1 | |
| Benzene SCHEMBL1403559 | 0.72 | HNF4A (0.69) | MEN1KMT2AHNF4ABCAT2FOLH1 | |
| Benzene SCHEMBL28480917 | 0.72 | HNF4A (0.69) | MEN1KMT2AHNF4ABCAT2FOLH1 | |
| SCHEMBL26624744 | 0.72 | HNF4A (0.69) | MEN1KMT2AHNF4ABCAT2FOLH1 | |
| SCHEMBL133057 | 0.72 | HNF4A (0.69) | MEN1KMT2AHNF4ABCAT2FOLH1 | |
| SCHEMBL4881052 | 0.72 | MEN1 (0.46) | MEN1KMT2AALDH1A1ALOX15MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904675-A | Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines | ZYMA SA (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0278908-A2 | Heterocyclic compounds | Zyma SA (CH) | 1988-08-17 | — | — | EP | disclosed |