SCHEMBL10150830

SCHEMBL10150830

O=C(OCCCCCCCCO)C(F)(F)S(=O)(=O)O/N=C(/c1ccccc1)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
HDAC1 Q13547 5/20 0.34
HDAC2 Q92769 5/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
HDAC3 O15379 2/20 0.32
HDAC4 P56524 2/20 0.32
HDAC7 Q8WUI4 2/20 0.32
HDAC10 Q969S8 2/20 0.32
HDAC11 Q96DB2 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC9 Q9UKV0 2/20 0.32
HDAC5 Q9UQL6 2/20 0.32
CES1 P23141 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10150850 0.87 TDP1 (0.35) TDP1HDAC1HDAC2CA12CA1
SCHEMBL10150854 0.87 TDP1 (0.35) TDP1HDAC1HDAC2CA12CA1
SCHEMBL10150847 0.86 TDP1 (0.43) TDP1HDAC1HDAC2CA12CA1
SCHEMBL10150831 0.86 TDP1 (0.43) TDP1HDAC1HDAC2CA12CA1
SCHEMBL10150835 0.83 PPARA (0.32) TDP1CES1PPARGPPARA
SCHEMBL12705110 0.82 POLB (0.33) TDP1PPARA
SCHEMBL10150848 0.82 POLB (0.33) TDP1PPARA
SCHEMBL12705092 0.81 POLB (0.37) TDP1CA1CA2ALDH1A1PPARG
SCHEMBL10150844 0.81 CA1 (0.32) TDP1CA1CA2
SCHEMBL775595 0.81 POLB (0.37) TDP1CA1CA2ALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same CYC1, UQCRB, CBR1 TDP1 4354/4885HDAC1 1351/4885HDAC2 1583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.