SCHEMBL10150848

SCHEMBL10150848

CCC(C)(C)C(=O)OCCOC(=O)C(F)(F)S(=O)(=O)O/N=C(\c1ccccc1)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.32
FKBP1A P62942 2/20 0.32
CHRM2 P08172 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
PRSS1 P07477 6/20 0.31
CTSG P08311 6/20 0.31
CTRB1 P17538 6/20 0.31
CMA1 P23946 6/20 0.31
AAK1 Q2M2I8 1/20 0.31
PPARA Q07869 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12705110 1.00 POLB (0.33) POLBNPSR1LMNAFKBP1ACHRM2
SCHEMBL10150854 0.96 TDP1 (0.35) POLBNPSR1LMNAFKBP1ACHRM2
SCHEMBL10150850 0.96 TDP1 (0.35) POLBNPSR1LMNAFKBP1ACHRM2
SCHEMBL10150852 0.86 HDAC1 (0.38) FKBP1ACHRM2CHRM1CHRM3CHRM4
SCHEMBL10150835 0.86 PPARA (0.32) POLBNPSR1LMNAPPARATDP1
SCHEMBL12705092 0.84 POLB (0.37) POLBNPSR1PPARATDP1
SCHEMBL775595 0.84 POLB (0.37) POLBNPSR1PPARATDP1
SCHEMBL10150830 0.82 TDP1 (0.38) PPARATDP1
SCHEMBL10150831 0.80 TDP1 (0.43) POLBPPARATDP1
SCHEMBL10150847 0.80 TDP1 (0.43) POLBPPARATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same CYC1, UQCRB, CBR1 POLB 607/4885NPSR1 2324/4885LMNA 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.