Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496086 | 0.85 | CRHR1 (0.43) | LIPCLIPGCRHR1TLR7HPGDS | |
| SCHEMBL10151931 | 0.74 | KDM4C (0.49) | LIPCLIPGCRHR1TLR7KDM4C | |
| SCHEMBL15635560 | 0.74 | PTGS1 (0.47) | LIPCLIPGTLR7KDM4C | |
| SCHEMBL2718820 | 0.74 | L3MBTL1 (0.55) | L3MBTL1HPGDSFFAR4KDM4ESCN9A | |
| SCHEMBL2713685 | 0.72 | L3MBTL1 (0.54) | L3MBTL1HPGDSKDM4E | |
| SCHEMBL2715161 | 0.72 | L3MBTL1 (0.54) | L3MBTL1HPGDSSCN9A | |
| SCHEMBL15350385 | 0.71 | FFAR4 (0.43) | LIPGL3MBTL1HPGDSFFAR4SCN9A | |
| SCHEMBL2714146 | 0.70 | POLB (0.65) | L3MBTL1HPGDS | |
| SCHEMBL496596 | 0.70 | KDM4C (0.54) | LIPCLIPGL3MBTL1KDM4CASPH | |
| SCHEMBL29644352 | 0.70 | L3MBTL1 (0.42) | L3MBTL1HPGDSFFAR4KDM4ESCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955697-B1 | 2-AMINOBENZAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) INHIBITORS USEFUL FOR THE TREATMENT OF PAIN OR BLADDER FUNCTION DISORDER | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |