SCHEMBL1015222

SCHEMBL1015222

C=CC(=O)OC(CC)[SiH2]OCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.36
HPGD P15428 1/20 0.35
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28476202 0.86 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1019122 0.84 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5958279 0.82 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21224454 0.81 TSHR (0.40) TSHRHPGDTHRB
SCHEMBL28467863 0.81 TSHR (0.39) TSHRHPGD
SCHEMBL1015617 0.79 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8853600 0.79 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5037177 0.79 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9056583 0.79 TSHR (0.34) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2496761 0.78 TSHR (0.37) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107398258-A A kind of Preparation method and use of surface organic modification modification vermiculite Composite 中国科学院新疆理化技术研究所 2017-11-28 CN claimed
EP-1833905-B1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER MICHELIN & CIE (FR) 2013-08-07 EP claimed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US claimed
US-20110021702-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-01-27 US claimed
US-7820771-B2 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S. A. (CH) 2010-10-26 US claimed
EP-1838765-B1 FUNCTIOANALISED POLYVINYLAROMATIC NANOPARTICLES MICHELIN RECH TECH (CH) 2010-08-04 EP claimed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US claimed
US-20090270558-A1 Functionalized Polyvinylaromatic Nanoparticles MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-10-29 US claimed
EP-2044148-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER Societe de Technologie Michelin (FR) 2009-04-08 EP claimed
EP-2041207-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES Societe de Technologie Michelin STM (FR) 2009-04-01 EP claimed
US-20080132644-A1 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-06-05 US claimed
WO-2008003435-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO claimed
WO-2008003434-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO claimed
CN-108333869-B Photosensitive composition, cured film, method for producing same, and display element, light-emitting element, and light-receiving element JSR株式会社 2023-07-18 CN disclosed
CN-110256630-A Phase difference material is formed with resin combination, orientation material and phase difference material 日产化学工业株式会社 2019-09-20 CN disclosed
CN-106030355-B Resin composition for forming phase difference material, alignment material, and phase difference material 日产化学工业株式会社 2019-06-18 CN disclosed
US-20090270558-A1 Functionalized Polyvinylaromatic Nanoparticles MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-10-29 US disclosed
EP-2044148-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER Societe de Technologie Michelin (FR) 2009-04-08 EP disclosed
US-20080132644-A1 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-06-05 US disclosed
WO-2008003435-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO disclosed