SCHEMBL9056583

SCHEMBL9056583

C=CC(=O)OC(CC)[SiH2]OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
HPGD P15428 1/20 0.33
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904873 0.87 THRB (0.33) TSHRHPGDTHRB
SCHEMBL5958279 0.83 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1019122 0.81 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1015222 0.79 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL8839124 0.79 TSHR (0.33) TSHR
SCHEMBL28467863 0.78 TSHR (0.39) TSHRHPGD
SCHEMBL1015617 0.77 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL8853600 0.77 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1678354 0.77 TSHR (0.34) TSHRTHRBALDH1A1
SCHEMBL28476202 0.77 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
CN-110120549-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN claimed
CN-110120550-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN claimed
CN-109206563-A Nanometer particle-modified cross-linked polymer and polymer dielectric and its preparation method and application 比亚迪股份有限公司 2019-01-15 CN claimed
CN-122035878-A Molded gel article and sintered article made therefrom 3M创新有限公司 2026-05-15 CN disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4622590-A1 CURABLE COMPOSITION FOR USE IN A PROCESS OF TREATING A DENTAL SITUATION IN THE MOUTH OF A PATIENT Solventum Intellectual Properties Company (US) 2025-10-01 EP disclosed
EP-4558086-A1 CURABLE COMPOSITION FOR PRODUCING TRANSPARENT ORTHODONTIC ATTACHMENTS Solventum Intellectual Properties Company (US) 2025-05-28 EP disclosed
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-10-31 US disclosed
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-27 US disclosed
CN-118401532-A High-purity polysiloxane macromer and preparation method thereof 盖列斯特有限公司 2024-07-26 CN disclosed
CN-110120549-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN disclosed
CN-109971122-A Epoxy resin molding material for encapsulation and electronic part apparatus 日立化成株式会社 2019-07-05 CN disclosed
CN-109249720-A Transfer member, ink jet recording method and ink-jet recording apparatus for transfer printing type ink-jet record 佳能株式会社 2019-01-22 CN disclosed
CN-108948062-A A kind of preparation method of the organo-silicon compound of the alpha-cyano acryloyl-oxy based structures containing anthracene protection 杭州师范大学 2018-12-07 CN disclosed
CN-105531298-B Electroconductive polymer manufacture monomer liquid and the manufacture method using its electrolytic capacitor 帝化株式会社 2017-11-28 CN disclosed
CN-103038063-B Intermediate transfer member for transfer ink jet recording CANON KK 2015-03-04 CN disclosed
EP-0716631-A1 PACKAGING MATERIAL INCLUDING A SILICA LAYER AND A POLYOLEFIN LAYER ELF ATOCHEM S.A. (FR) 1996-06-19 EP disclosed
WO-1996000656-A1 PACKAGING MATERIAL INCLUDING A SILICA LAYER AND A POLYOLEFIN LAYER ELF ATOCHEM S.A. (FR) 1996-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials CDH1, F12, ACTN1 TSHR 4762/4885HPGD 336/4885THRB 3551/4885
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A TSHR 705/4885HPGD 4304/4885THRB 739/4885
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials CDH1, F12, ACTN1 TSHR 4762/4885HPGD 336/4885THRB 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.