Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017997 | 0.89 | L3MBTL1 (0.58) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL725034 | 0.84 | KDM4E (0.50) | ADORA3ADORA2AADORA1MAPTALDH1A1 | |
| SCHEMBL25401921 | 0.80 | KDM4C (0.50) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL30585054 | 0.80 | KDM4C (0.50) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL30584957 | 0.77 | HDAC6 (0.52) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL25403016 | 0.76 | MRGPRX4 (0.46) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL14313072 | 0.75 | ADORA3 (0.43) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL24015544 | 0.73 | L3MBTL1 (0.58) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL17458934 | 0.73 | L3MBTL1 (0.58) | L3MBTL1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL3616273 | 0.73 | MAPT (0.65) | L3MBTL1ADORA2AADORA2BADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001890-B1 | TETRAHYDROPYRIDOTHIENOPYRIMIDINE COMPOUNDS AND USE FOR THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | BAYER SCHERING PHARMA AG (DE) | 2011-01-12 | — | — | EP | disclosed |