Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HOGA1 | Q86XE5 | 2/20 | 0.44 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932305 | 0.89 | HOGA1 (0.48) | HOGA1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL9289211 | 0.83 | HOGA1 (0.42) | HOGA1 | |
| SCHEMBL24137928 | 0.73 | HOGA1 (0.33) | HOGA1 | |
| SCHEMBL20873288 | 0.73 | HOGA1 (0.32) | HOGA1 | |
| B-D-Galactose SCHEMBL79721 | 0.73 | LGALS3 (0.58) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| B-D-Galactose SCHEMBL21123450 | 0.73 | LGALS3 (0.58) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| D-Allose SCHEMBL60362 | 0.73 | LGALS3 (0.58) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| B-D-Galactose SCHEMBL10050863 | 0.73 | LGALS3 (0.58) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| B-D-Galactose SCHEMBL10050865 | 0.73 | LGALS3 (0.58) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| B-D-Galactose SCHEMBL23758905 | 0.73 | LGALS3 (0.58) | LGALS1LGALS3LGALS9LGALS8PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165282-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165282-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | MRPL21, QARS1, NQO2 | HOGA1 1144/4885LGALS1 3297/4885LGALS3 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.